Tadalista 10 is the treatment for erectile dysfunction, or ED, one of the most dangerous disorders that plague men. Tadalafil belongs to the pharmacological class of phosphodiesterase type 5 inhibitors. A group of substances with similar modes of action is called a class of medicines. Tadalafil can last up to 36 hours and as early as 30–60 minutes before engaging in sexual activity. It can be taken with or without meals. It's important to keep in mind that the drug may act more slowly than usual after some meals, particularly ones high in fat. If your pharmacist has one available, read the Patient Information Leaflet before using it each time you get a refill.