Modvigil 200 contains modafinil, which works in the brain by affecting neurotransmitters that regulate wakefulness and attention. Although the exact mechanism of action is still not fully understood, modafinil is thought to increase levels of neurotransmitters in the brain, including dopamine, norepinephrine, and histamine.

Modvigil 200 increases dopamine release, primarily by inhibiting dopamine reuptake, which helps improve mood, focus, and attention. It also affects the hypothalamus, the part of the brain responsible for regulating sleep and wakefulness, by increasing levels of histamine and orexin, which promote wakefulness. This combination of effects helps people stay awake and alert, helping to treat conditions such as narcolepsy, sleep apnea, and shift work sleep disorder.