Cranberry Juice Benefits Female Sexually is rich in antioxidants like vitamin C, which can support immune function and overall health. Drinking cranberry juice before bed could provide a dose of antioxidants that help fight free radicals overnight. Cranberry juice contains water, so it can contribute to overall hydration. Staying hydrated overnight is important, but you should be mindful not to drink too much liquid, as it could cause you to wake up needing to go to the bathroom in the middle of the night. Cranberry juice is acidic, and consuming acidic beverages right before bed could cause heartburn or acid reflux in some people, particularly if they have a history of gastrointestinal issues.